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Trial Name:

Cervical Cancer

Intro: This research study is designed to determine whether combining the drug Tirapazamine with Cisplatin during radiation therapy increases the length of time that patients with cancer of the cervix live without their cancer coming back compared to patients who receive Cisplatin and radiation therapy without receiving Tirapazamine.
Condition:
Description: This research study is designed to determine whether combining the drug Tirapazamine with Cisplatin during radiation therapy increases the length of time that patients with cancer of the cervix live without their cancer coming back compared to patients who receive Cisplatin and radiation therapy without receiving Tirapazamine. Cisplatin and radiation therapy are standard treatments that are given to treat cancer of the cervix. Tirapazamine is an investigational drug. Eligible participants will be assigned to Group 1 or Group 2 by chance. Participants who are enrolled in Group 1 receive Cisplatin along with external and internal radiation therapy. Participants enrolled in Group 2 receive Cisplatin and Tirapazamine along with external and internal radiation. There is an equal chance of being assigned to Group 1 or Group 2.
Criteria: Participants must be 18 years of age or older and have a specific type of cancer of the cervix. Participants must have adequate bone marrow, liver and kidney function. Participants must meet the criteria for chemotherapy and pelvic radiation treatment. Participants of childbearing potential must have a negative pregnancy test and must agree to use an effective form of contraception.
Contact: For information or to register for screening in this trial please call HealthMatch at (216) 844-5000, or complete and submit the form below.

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All information regarding participation in Clinical Trials is treated with the utmost confidentiality. University Hospitals Case Medical Center and the Division of Clinical Research recognize and respect the confidentiality of this information. Access to information related to clinical trials and their participants is restricted to authorized clinical trials personnel only.

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