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Health Encyclopedia

Macroamylasemia

Definition

  

Macroamylasemia is the buildup of a molecule, called macroamylase, in the blood.


Causes, incidence, and risk factors

  

Macroamylase is a molecule that consists of an enzyme, called amylase, bound to a protein. Because it is relatively large, macroamylase is filtered very slowly from the blood by the kidneys.

Macroamylasemia has been associated with:

  • Celiac disease
  • Ulcerative colitis
  • Rheumatoid arthritis
  • Lymphoma
  • HIV infection
  • Monoclonal gammopathy

Symptoms

  

Macroamylasemia does not cause symptoms.


Signs and tests

  

Macroamylasemia causes a high amylase blood level reading.

Macroamylasemia can be confused with acute pancreatitis, which also causes high levels of amylase in the blood.

Macroamylasemia can be diagnosed by measuring amylase levels in the urine. Urine levels of amylase would be low. This is in contrast to acute pancreatitis, in which urine amylase levels will be high.


Treatment

  


Support Groups

  


Expectations (prognosis)

  


Complications

  


Calling your health care provider

  


Prevention

  


 
Review Date: 10/18/2006
Reviewd By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Jefferson Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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